Logan, Utah – September 27, 2004 –
Perbio Science, a wholly owned subsidiary of Fisher Scientific International Inc. (NYSE: FSH), announces a new medium developed for the murine myeloma cell line, NS0. HyClone HyQ® CDM4NS0™ is the first complete medium on the market to support NS0 cell culture. The medium requires no cholesterol or GS supplementation. HyQ CDM4NS0 is chemically-defined, containing no animal derived components or undefined hydrolysates. In multiple evaluations using GS and non-GS NS0 transfectomas this medium provides 2-10 times higher MAb yields than traditional cultures using serum-free hybridoma media requiring multiple supplements. It is available as a liquid formulation without L-glutamine, and in a dry powdered formulation for on-site hydration in existing media formulation facilities.

HyClone is a leading brand in cell-culture technology, offering a line of serum-free media for the following cell lines: Chinese hamster ovary (CHO), hybridoma and myeloma, gene therapy (e.g., HEK 293, PER.C6™ [Crucell NV]), insect, and viral vaccine (e.g., Vero, MDCK). HyClone serum-free media received the prestigious 2003 Frost and Sullivan Drug Discovery Product of the Year.

For more information, contact:
Brandon Pence, Product Manager, HyClone, Phone: 435-792-8000, e-mail: brandon.pence@perbio.com

About Perbio Science and HyClone
HyClone is a brand of Perbio Science, a wholly owned subsidiary of Fisher Scientific International Inc. (NYSE: FSH), and part of Fisher’s Biochemicals group. HyClone is a leading global brand of cell-culture and bioprocessing systems for life-science research and protein-based drug production. HyClone is widely known as the premier brand of quality sera for cell culture, classical media, serum-free media and protein-free media. In addition, HyClone is a leading brand of flexible, single-use containers, BioProcess Container™ (BPC®) systems, which are sterile, disposable bags specifically designed for transporting, mixing, dispensing, and storing sterile liquids and powders. For more information about HyClone brand products call 435-792-8000; or e-mail info@hyclone.com; or visit the Web site at www.hyclone.com.

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