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Thermo
Fisher Scientific Expands Stem-Cell Research Platform with Tools for Adipogenic
Differentiation LOGAN, Utah, (Feb. 25, 2008) – Thermo Fisher Scientific Inc., the world leader in serving science, has introduced a new set of cell-culture products to support differentiation of two important stem-cell lines for research and therapeutic applications. The offering combines the Thermo Scientific AdvanceSTEM Adipogenic Differentiation Kit with human bone marrow mesenchymal and adipose-derived mesenchymal stem cells from Cellular Engineering Technologies (CET). The AdvanceSTEM Adipogenic Differentiation Kit was developed specifically to support the differentiation of human bone marrow mesenchymal and adipose-derived mesenchymal stem cells into adipocytes. Adipocytes are fat cells that are important in the study of metabolic dysfunction and fat gain in humans. They are also used to treat burn victims by replacing fat padding that underlies sensitive tissues, and to treat people who have lost fat due to chronic disease. By using the differentiation kit, scientists can develop adipocytes more quickly and easily than with other methods. The kit includes media that contains specific growth factors to direct the stem cell differentiation, along with a cell-culture supplement. Only one step — mixing the media and supplement together — is required before adding the stem cells for differentiation. “The kit takes the guesswork out of differentiation and saves valuable time in research and development of adipocytes,” said Alain Fairbank, research market manager for BioProcess Production at Thermo Fisher Scientific. “This enables scientists to accelerate work that will ultimately benefit people who are injured or suffer from disease.” Thermo Fisher Scientific has tested and qualified the AdvanceSTEM Adipogenic Differentiation Kit with the CET stem cells so researchers do not have to perform additional testing. CET’s human bone marrow-derived and adipose derived mesenchymal stem cells are grown in media and sera without additional growth factors so their differentiation potential is not compromised. All cells are characterized with a panel of known markers and analyzed by flow cytometry to ensure more than 95 percent purity. Through an agreement with CET, Thermo Fisher Scientific is marketing and delivering the stem cell lines worldwide as a complementary offering to the differentiation kit. This new offering expands the Thermo Scientific HyClone AdvanceSTEM range of cell-nutrition products developed specifically for applications in stem-cell research. The AdvanceSTEM Differentiation Kit and CET Cells are part of the Thermo Scientific Stem Cell Excellence portfolio, an end-to-end workflow solution that incorporates essential instruments, equipment, consumables, reagents and media, services and software tailored to the needs of stem-cell laboratories. Learn more at www.thermo.com/stemcell Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving science. About Thermo
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