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Press Release

HyClone Launches Metabolically Designed Serum-Free Media for Gene Therapy Cell Lines

Logan, Utah (May 1, 2003)-

HyClone announces the release of two new media products for cell lines commonly used in gene therapy research and production applications. HyQSFM4HEK293 is a versatile serum-free medium developed to support high adenoviral vector and recombinant protein production in human embryonic kidney (HEK) 293 cells. HyQCDM4Retino is a high performance chemically-defined medium developed to increase process yields in the industrial manufacture of adenoviral vectors and recombinant proteins using PER.C6 (PER.C6 is a trademark of Crucell NV) and retina-derived cells. These new media are available in liquid and powdered formulations.

The launch further strengthens HyClone’s position as the premier global supplier of serum-free media. HyClone offers a complete line of serum free media for major cell culture applications including Chinese Hamster Ovary (CHO), hybridoma and myeloma, insect, and cells used in viral vaccine production, such as Vero and MDCK.

For more information, contact: Brandon Pence, Serum-Free Media Product Manager, 435-792-8000 or brandon.pence@perbio.com.

HyClone is a global manufacturer of serum, liquid and powdered media, process liquids, reagents, and sterile liquid handling systems to support research and production of biopharmceuticals. HyClone is owned by Perbio Science. For more information about HyClone, visit the web site at www.hyclone.com

Perbio Science AB is an international biotech company based in Sweden whose customers are found within research institutions, pharmaceutical companies and diagnostics manufacturers. The majority of the company’s operations take place in the USA. Perbio Science develops products within the areas of Bioresearch, Cell Culture and Medical Devices. The group has 1,155 employees with offices in Sweden, USA and a number of other countries. The head office is in Helsingborg. More information regarding Perbio Science can be found at www.perbio.com.