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US Defined Fetal Bovine Serum

Defined Fetal Bovine Serum (FBS), US Origin
SH30070.01 50 mL
SH30070.02 100 mL
SH30070.03 500 mL
Defined Fetal Bovine Serum (FBS), US Origin, Heat Inactivated
SH30070.01HI 50 mL
SH30070.02HI 100 mL
SH30070.03HI 500 mL
Defined Fetal Bovine Serum (FBS), US Origin, Irradiated
SH30070.03IR 500 mL

Defined FBS is the highest quality FBS available and is widely used by those cell culturists who have a concern for viral contaminants and require an extensive biochemical profile. Defined FBS is filtered through serial 40nm (0.04 µm) pore-size rated filters, which are the most retentive filters used in commercial FBS production. This type of filtration is a practical, cost-competitive method of viral load reduction. Data shows that 40nm filtration will remove as many as eight logs of viral challenge. This is a dramatic improvement over the current industry standard of using filters with mean pore sizes of 100nm. Studies demonstrate that this filtration regimen has no adverse effect on cell growth. Finished Defined FBS has over 50 components analyzed and the results are included on the Certificate of Analysis and the Biochemical Assay.

Assays (subject to change without notice): Progesterone, Insulin, Cholesterol, High Density Lipo-Protein Cholesterol, Low Density Lipo-Protein Cholesterol, Triglycerides, Gamma Globulin, Phospholipids, Alkaline Phosphatase, Lactate Dehydrogenase, Glutamic Pyruvic Transaminase (SGPT), Glutamic Oxaloacetic Transaminase (SGOT), Thiamine (B1), Riboflavin (B2), Pyridoxine (B6), Nicotinic Acid (Niacin), Vitamin H (Biotin), Vitamin A (Retinol), Carotene, Total Vitamin E (Tocopherol), Cyanocobalamine (B12), Pteroylglutamic Acid (Folate), Vitamin C, 1,25 Dihydroxy Vitamin D, pH, Total Protein, Albumin, Blood Urea Nitrogen, Creatinine, Total Bilirubin, Inorganic Phosphorus, Osmolality, Iron, Selenium, IgG, Sodium, Potassium, Calcium, Chloride, Magnesium, Glucose, Copper, Total Iron Binding Capacity (TIBC), and Percent Saturation.

Test Specification
Endotoxin (Limulus Amebocyte Lysate - Gel Clot) <10 EU/mL
Hemoglobin (spectophotometric) <10 mg/dl
Sterility Testing Current USP & EP
Bacteria & Fungi No Growth
Virus Testing (9 CFR 113.53)
Flourescent Antibody
Bluetongue Not Detected
Bovine Adenovirus Not Detected
Bovine Parvovirus Not Detected
Bovine Respiratory Syncytial Virus Not Detected
Bovine Viral Diarrhea Virus Not Detected
Rabies Not Detected
Reovirus Not Detected
Cytopathogenic Agents - e.g IBR Not Detected
Hemadsorbing Agents - e.g. PI3 Not Detected
Mycoplasma
Large Volume, Direct Culture Not Detected
Hoechst DNA Stain Not Detected
Certificate of Suitability Included

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Fetal Bovine Serum
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  - New Zealand
  - USDA Tested
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  - US Defined EMEA Conforming
  - US Characterized EMEA Conforming
  - Australian EMEA Conforming
  - New Zealand EMEA Conforming
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