As biotherapeutics are desired more closely representative of their native form, the application of human-derived cell lines for recombinant protein, monoclonal antibodies and gene therapy viral vectors has rapidly emerged. Thermo Scientific products include high performing serum-free media capable of providing optimal cell culture conditions for HEK 293 and PER.C6® cells in these applications.These media have been developed through the Metabolic Pathway Design approach to ensure that the needs of human-derived cell lines are met to enable the highest level of productivity.

Hyclone CDM4HEK293™
HyClone CDM4HEK293 is a chemically-defined, animal derived component free and protein-free cell culture medium designed to support the growth of HEK 293 cultures, and promote adenovirus and recombinant protein production.This regulatory-friendly medium was developed to support high cell density and specific cell productivity in suspension cultures.

Hyclone SFM4Transfx-293™
HyClone SFMTransfx-293 is a serum-free, animal derived component free medium designed to support the growth of HEK 293 cultures and promote transfection using lipofection or similar methods.This regulatory-friendly medium was developed to support high transfection efficiency, productivity and cell density in suspension cultures.

Hyclone CDM4PERMAb™
HyClone CDM4PERMAb is a chemically-defined medium containing no animal derived components.This high performance cell culture medium has been developed to increase process yields in the production of human antibodies and recombinant proteins using PER.C6® technology. It has been successfully tested in a variety of applications, including fed-batch bioreactors.