On the Cutting Edge of Technology: HyNetics™
In November 2002, HyClone completed its first liquid production utilizing its new, validated HyNetics module for the hydration of powdered media and buffers.

Developed in a joint venture with Kinetics, HyClone’s state-of-the-art HyNetics module is housed in a segregated Class 100,000 clean room. The module manufactures products by employing single-use product contact surfaces and provides for the production of sterile-filtered liquids from powders in a closed system— from automated hydration and mixing to dispensing and packaging. HyNetics modules are available for purchase and installation at biopharmaceutical production plants and research institutions. The module provides a safe and dependable method of hydrating powdered media and reagents.

Utilizing disposable contact surface manufacturing in the HyNetics modules eliminates clean-in-place, steam-in-place (CIP/SIP) and cleaning validation procedures. The resulting benefits are reduced costs and decreased turn-around time. The closed system and disposable contact surfaces also prevent the possibility of cross-contamination in a multiproduct facility.

Two variable volume support vessels make up the core of the HyNetics production module. One has a maximum lot size capacity of 3,000 L and the other, 10,000 L. Actual lot sizes can range from 500 to 10,000 L. HyNetics systems are available in a variety of sizes.