CHO Cell Culture Platform Product List Product Inserts  - HyClone SFM4CHO-A  - HyClone CDM4CHO  - HyClone SFM4CHO  - HyClone SFM4CHO-Utility HyClone CDM4CHO Brochure* HyClone SFM4CHO and HyClone SFM4CHO-Utility Brochure* Click Here to Order Hard Copy Versions

The CHO cell culture platform has led the biopharmaceutical industry in its use of serum-free media (SFM). HyClone is an industry leader and continues to develop a selection of superior media to meet its clients’ needs for CHO cell culture HyClone has developed a selection of serum-free media for the unique needs of CHO cells.

HyClone®SFM4CHO-A™ (SH30820, SH30821, SH30819)
Thermo Scientific HyClone SFM4CHO-A is a protein-free medium containing no animal derived components. This regulatory-friendly medium is developed through Metabolic Pathway Design? to support the growth of multiple CHO cell clones and the production of a variety of recombinant proteins in adherent cultures. It has been successfully tested in a variety of culture systems including T-flasks and microcarrier cultures.

HyClone®CDM4CHO™ (SH30557, SH30558, SH30556)
The Premier Chemically-Defined Medium for Therapeutic rProtein Production in CHO Cells
HyClone CDM4CHO is a chemically-defined medium containing no animal derived components.This regulatory-friendly medium is developed through Metabolic Pathway Design™ to increase process yields in the manufacture of recombinant proteins using a variety of CHO cell clones. HyClone CDM4CHO has been successfully tested in a variety culture systems, including T-flasks, shaker flasks and bioreactors, including fed-batch and perfusion.

HyClone CDM4CHO contains Pluronic® F68 and L-Glutamine, and does not contain phenol red. It is also available without L-Glutamine to support the GS gene expression system.

HyClone®SFM4CHO™ (SH30549, SH30548, SH30518)
The Premier Protein-Free Medium for Therapeutic rProtein Manufacturing
This high performance cell culture medium is developed through Metabolic Pathway Design™ to increase the process yields for the industrial manufacturing of recombinant proteins for therapeutic use in a variety of CHO cells.

HyClone SFM4CHO is a protein-free formulation that contains no components of bovine origin and has been designed for high performance in a variety of culture vessels, including bioreactors. It is formulated using our proprietary lipid complexing process for enhanced stability and growth promotion of various CHO cell lines. HyClone SFM4CHO contains L-Glutamine and Pluronic® F68, and does not contain phenol red. It has been designed to support the DHFR selection/amplification system, and is also available without L-Glutamine to support the GS gene expression system.

HyClone SFM4CHO™-Utility (SH30516, SH30517)
The Preferred Protein-Free Medium for rProtein Production in Research
This versatile protein-free cell culture medium is developed through Metabolic Pathway Design™ to support the growth of multiple CHO cell clones and production of a variety of recombinant proteins. It enables superior growth of many CHO cells with minimal adaptation.

HyClone SFM4CHO-Utility is ideally suited for the cost-effective manufacturing of recombinant proteins for academic and industrial research, genomics and proteomics, drug target screening and validation, and manufacturing of preclinical lots. It is formulated using our proprietary lipid complexing process for enhanced stability and broad-spectrum growth promotion.

HyClone SFM4CHO-Utility contains Pluronic® F68, and does not contain phenol red. It has been designed to support the DHFR selection/amplification system. This protein-free medium has been successfully tested in a variety of culture systems including T-flasks, spinner and shaker flasks, roller bottles and bioreactors.

In addition to the aforementioned products, HyClone continues to offer its early generation serum-free CHO media. HyClone PF CHO™ and HyClone PF CHO LS™, HyClone’s first two protein-free products, have been successfully tested in a variety of applications and accepted in numerous research and biopharmaceutical settings. HyClone’s first two products for the CHO cell culture platform, HyClone CCM5™ and HyClone SFX-CHO™, have been designed for anchorage-dependent and suspension CHO cells, respectively.

CHO Cell Culture products available:

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