Multipotent stem cells, sometimes called adult stem cells (ASCs), have been found to persist in their undifferentiated state in embryonic and adult tissues. These cells can be derived from most tissues and, depending on their origin, have different properties and capacity for generating a variety of progeny. However, unlike embryonic stem cells, they are limited in quantity, have limited life span in culture and have a limited number of cell types into which they can differentiate.

Mesenchymal stem cells represent an interesting and widely used stem cell type, possessing the ability to differentiate into a variety of cell types, including adipocytes, chondrocytes, osteocytes, cardiomyocytes, neurons and many others.

The Thermo Scientific HyClone AdvanceSTEM line of stem cell culture products has been developed specifically for applications in stem cell research. The line comprises numerous products designed to support a wide range of applications such as the expansion and maintenance of undifferentiated murine embryonic and human adult mesenchymal stem cells, to the directed differentiation of mesenchymal stem cells into such cell types as neurons,
adipocytes, chondrocytes, and osteocytes.

Recently, Thermo Fisher Scientific entered into an agreement with Cellular Engineering Technologies (CET) to provide a wide array of human non-embryonic stem cells, growth media and differentiation media.

This agreement covers the production and marketing of human non-embryonic stem cells, growth media used to grow these cells and differentiation media used to convert the stem cells into other types of human cells. This partnership was formed in response to growing demand among researchers for human non-embryonic stems cells, which have shown great promise as a potential treatment for such conditions as Diabetes, Cardiovascular Failure and Parkinson's disease, among many others.

All CET stem cells are characterized and tested with a panel of known stromal, stem, and hematopoietic markers. Each system is analyzed by flow cytometry to ensure > 95% purity. All stem cells test negative for HIV-1, HIV-2, Hepatitis B, and Hepatitis C.

All CET stem cells are only grown in media and serum with no additional growth factors used prior to distribution, in order not to compromise the differentiation potential.

About Cellular Engineering Technologies

CET is a biotechnology tissue engineering company, which combines engineering with life science for preclinical drug discovery. CET specializes in stem cells obtained from human non-embryonic sources, such as fat collected during liposuction procedures, umbilical cords, umbilical cord blood, and placentas collected after full-term deliveries. The company was founded by Dr. Alan Moy, CEO, in 2000 and is Iowa's premier non-embryonic stem cell company.

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