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You may have known
us as HyClone - a business with nearly 40 years of experience in the cell-culture
industry. Now we have even more to offer you as part of the new Thermo
Fisher Scientific, created by the merger of Thermo Electron and Fisher
Scientific in November of 2006. Transitioning to the Thermo Scientific
brand, HyClone is committed to providing researchers globally with the
most advanced tools to facilitate and advance their research.
As a leading supplier
of HyClone sera, media, and other cell culture reagents, Thermo Fisher
Scientific strives to keep abreast of innovations and advances in cell
culture and to obtain a degree of knowledge and expertise in the major
areas of research utilizing cell culture. One such area is the culture
of ESCs. The number of studies using ESCs has increased considerably over
the past few decades with a corresponding increase in the demand for specialty
sera and media specific for these applications.
The market and financial
strength of this organization enhances our ability to innovate and respond
to your evolving needs. And, the combination creates a broad portfolio
of complementary products and services that can be integrated with ours
to improve your efficiency.
Thermo Fisher Scientific
is privileged to support your endeavors in stem cell research. We are
committed to providing you with the highest quality products to help you
advance your research in the understanding of these cells, which we strongly
believe will better the human condition by bringing new therapeutics and
cures for human disease.
While our product labels and packaging have transitioned to the Thermo
Scientific brand, our commitment to you and the integrity of our products
will continue.
Stem cell research has rapidly advanced during the past several years,
primarily due to the promise of therapeutics derived from stem cells.
Stem cells are defined by two criteria common to all stem cells: Their
ability for prolonged proliferation in an undifferentiated state, or "self-renewal,"
and, their ability to differentiate into more than one type of specialized,
differentiated cell type.
Embryonic stem cells (ESCs) are pluripotent stem cells that have been
derived from the inner cell mass of a blastocyst-stage embryo. They have
the ability to differentiate from the three germ layers of cells - ectoderm,
endoderm, and mesoderm - into cells of all types found in the adult mammal.
Able to maintain very long term growth in culture, these cells also have
the ability to maintain a normal karyotype and retaining all the pluripotency-associated
markers.
First isolated in 1981, murine embryonic stem cells, or “ES cells,”
are used to produce mouse models of human disease that aid in the understanding
of and in the development of therapies for genetic diseases in humans.
The discovery and use of mouse ES cells and associated technology that
allows the precise modification of individual genes has had such a major
impact on biomedical research that the three scientists who laid the ground
work for the use of mouse ES cells and the associated gene targeting technology
were awarded the 2007 Nobel Prize in Medicine. We are now pleased to offer
murine embryonic stem cells from Primogenix, Inc.
Somatic stem cells, sometimes called adult stem cells (ASCs), have been
found to persist in their undifferentiated state in embryonic and adult
tissues. These cells can be derived from different parts of the body and,
depending on their origin, have different properties and capacity for
generating a variety of progeny. However, they are limited in quantity,
and have a limited number of cell types that they can differentiate into.
Now, through our agreement with Cellular Engineering Technologies, we
offer a comprehensive line of Human Somatic Stem Cells as well as specialized
formulations for the expansion and differentiation of these cells.
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